• Medical Research Institute - Sri Lanka

    The premier medical research institute in Sri Lanka
  • Medical Research Institute - Sri Lanka

    The premier medical research institute in Sri Lanka
  • Medical Research Institute - Sri Lanka

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Research

The Clinical Virology Laboratory has a long record of clinical research in collaboration with clinicians and surgeons, and colleagues at other institutions.

List of Research Articles: 

  1. Single-Reaction, Multiplex, Real-Time RT-PCR for the Detection, Quantitation, and Serotyping of Dengue Viruses

doi: 10.1371/journal.pntd.0002116

  1. Profound plasmacytosis in a patient with dengue

https://doi.org/10.1007/s12185-013-1452-3

  1. Comparison of the FDA-Approved CDC DENV-1-4 Real-Time Reverse Transcription-PCR with a Laboratory-Developed Assay for Dengue Virus Detection and Serotyping 

doi: 10.1128/JCM.01359-13

  1. Multiplex Nucleic Acid Amplification Test for Diagnosis of Dengue Fever, Malaria, and Leptospirosis

doi: 10.1128/JCM.00341-14

  1. Commutability of the Epstein-Barr Virus WHO International Standard across Two Quantitative PCR Methods

DOI: 10.1128/JCM.01676-14 

  1. Homotypic Dengue Virus Reinfections in Nicaraguan Children

DOI: 10.1093/infdis/jiw099 

  1. Laboratory diagnosed dengue among clinically suspected febrile patient-samples at National Dengue Laboratory, Sri Lanka
  2. Clinical evaluation of a single-reaction real-time RT-PCR for pan-dengue and chikungunya virus detection 

DOI: 10.1016/j.jcv.2016.01.007 

  1. Varicella zoster virus as a cause of infectious encephalitis in a cohort of Sri Lankan patients

DOI: 10.4038/cmj.v61i4.8392 

  1. Diagnosis of Zika virus infection on a nanotechnology platform

  DOI: 10.1038/nm.4302 

  1. Screening for Cytomegalovirus Infection During Pregnancy in a Teaching Hospital, Western province, Sri Lanka

DOI: 10.4038/sljog.v39i4.7825

  1. Epstein-Barr virus infection in a group of post-renal transplant patients in two main renal transplant centers in a South Asian country
  2. Clinical evaluation of a single-reaction real-time RT-PCR for pan-dengue and chikungunya virus detection

DOI: 10.1016/j.jcv.2016.01.007

  1. Rotavirus infection among hospitalized children under five years of age with acute watery diarrhea in Sri Lanka

DOI: 10.1016/j.vaccine.2018.03.062 

  1. Post-Transplant Lymphoproliferative Disorder (PTLD); A Descriptive Cross-Sectional Study Describing the Presence of Associated Factors for PTLD in a Cohort of First Year Post Renal Transplant Patients in Sri-Lanka

doi: 10.1111/tri.12744.

  1. Viral etiology and clinico-epidemiological profile of clinically suspected acute viral encephalitis

https://doi.org/10.1016/j.ijid.2009.03.035

  1. Retrospective analysis of Hepatitis B serology profiles of a cohort of Hepatitis B Surface antigen positive patients, Sri Lanka

http://doi.org/10.4038/joshhm.v4i0.71

  1. Seroprevalence of Hepatitis B and C virus Infection Among Clinically Suspected Patients At State Sector Hospitals In Sri Lanka; A Laboratory Based Retrospective Study

DOI:  10.1080/23744235.2019.1640387

  1. The laboratory investigation of a measles outbreak in the eve of its elimination in Sri Lanka

DOI: 10.1016/j.jcv.2019.104230 

  1. Corrigendum to “The laboratory investigation of a measles outbreak in the eve of its elimination in Sri Lanka” [J. Clin. Virol. 122 (2020) 104230

DOI: 10.1016/j.jcv.2019.104230

  1. Dengue Virus and Yellow Fever Virus Detection Using Reverse Transcription–Insulated Isothermal PCR and Comparison with Real-Time RT-PCR

DOI: 10.4269/ajtmh.19-0892 

  1. Guidelines on Microbiological Investigations, Antimicrobials, Vaccines, Infection Prevention and Control Practices in Haematopoietic Stem Cell Transplantation Sri Lanka

https://slmicrobiology.lk/2021/09/17/guidelines-on-microbiological-investigations-antimicrobials-vaccines-infection-prevention

  1. Distribution of Dengue Virus Serotypes during the COVID 19 Pandemic in Sri Lanka

DOI: 10.23880/vij-16000299

  1. Laboratory Based Preliminary Study on Anti-SARS-CoV-2 Antibody Response among State Sector Healthcare Workers in a Single District in Sri Lanka

DOI: 10.23880/vij-16000300

  1. Recent Trends in Dengue Virus Infection; An Analysis of Virological, Clinical and Laboratory Profiles of Patients with Dengue Virus Infection in the Center for Clinical Management of Dengue Fever and Dengue Hemorrhagic Fever, Sri-Lanka

DOI: 10.23880/vij-16000301

  1. Laboratory response to an infant with suspected measles vaccine associated fever and rash in Sri Lanka

https://doi.org/10.1016/j.imj.2023.02.001

  1. Laboratory diagnosis, molecular characteristics, epidemiological and clinical features of an outbreak of measles in a low incidence population in Australia

 DOI: 10.1016/j.jcv.2012.02.025 

  1. Congenital toxoplasmosis over 10 years in a low-incidence population

DOI: 10.5694/mja11.11237 

  1. Measles and SSPE: occurrence and pathogenesis
  1. The reliability of HBV core antibody in serological screening for hepatitis B virus

DOI: 10.1097/PAT.0b013e3283631cf9 

  1. Molecular Epidemiology of Influenza A(H1N1)pdm09 Virus among Humans and Swine, Sri Lanka

doi: 10.3201/eid2012.140842

  1. BK virus vireamia and viruria among a group of post kidney transplant patients in Sri Lanka

  DOI: 10.4038/cmj.v62i2.8480 

  1. Comparison of real time PCR with the Culture method for detecting Salmonella spp in raw chicken.
  2. Human bocavirus infection in a selected group of children with severe acute respiratory symptoms. . Bulletin of the Sri Lanka College of Microbiologists. OP-16, pp 15 August 2017, 15 (1)
  3. Sri Lanka Medical Association Guidelines and Information on Vaccines Sixth Edition 2017
  4. Seasonality of Respiratory Syncytial Virus from respiratory samples received at National Influenza Centre (NIC) MRI from 2011 to 2014
  5. A preliminary study on VP1 gene based genotyping of BK virus in a cohort of renal transplant patients in Sri Lanka

  DOI: 10.4103/ijmr.IJMR_79_20 

  1. Susceptibility of pregnant mothers to varicella- Do we need special actions?

https://doi.org/10.1186%2Fs12879-019-3996-1

  1. Prevalence of BK virus among renal transplant recipients in a tertiary care hospital in Sri Lanka

DOI: 10.4038/cmj.v63i3.8716 

  1. Susceptibility for varicella and factors associated with immunity among pregnant women in a tertiary care hospital in Sri Lanka- A cross-sectional study

https://doi.org/10.1186/s12879-019-3996-1

  1. Outbreak of respiratory tract infection among children in Southern Province

doi: 10.1136/bmjopen-2020-040612.

  1. Outbreak of severe acute respiratory infection at Prajapathi Children’s Orphanage at Panadura
  2. Evaluation of rapid immunochromatographic assays for the detection of selected respiratory viruses during an outbreak

Annual Academic Sessions of Sri Lanka College of Mircobiologists

  1. Infleunza surveillance activities in Sri Lanka
  2. Subacute sclerosing panencephalitis: a rare cause of acute cortical visual impairment in an adult

DOI: 10.1177/0049475520939325 

  1. Establishment of an in-house SARS CoV-2 real-time PCR and investigation of first few suspected cases of COVID-19 in Sri Lanka

Annual Academic Sessions of Sri Lanka College of Mircobiologists

  1. Viral kinetics in serial respiratory samples and clade of the virus of the first positive (SARS CoV-2) patient reported in Sri Lanka

Annual Academic Sessions of Sri Lanka College of Mircobiologists

  1. Outbreak of severe acute respiratory infection in Southern Province, Sri Lanka in 2018: a cross-sectional study

DOI: 10.1136/bmjopen-2020-040612 

  1. Introduction of an in-house real-time PCR assay to detect severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) in Sri Lanka: challenges and issues
  2. Guidelines on Microbiological Investigations, Antimicrobials, Vaccines, Infection Prevention and Control Practices in Haematopoietic Stem Cell Transplantation Sri Lanka
  3. Molecular characterization of BK virus detected in renal transplant patients in Sri Lanka: a preliminary study

DOI: 10.4103/ijmr.IJMR_79_20 

  1. A preliminary study on the UL97 gene of cytomegalovirus isolated from patients suspected of ganciclovir resistance in Sri Lanka

DOI: http://doi.org/10.4038/sljid.v13i1.8537

  1.  Sociodemographic and clinical characteristics of SARS-CoV-2 infected population during the second and third epidemiological waves in Sri Lanka. Asian Pac J Trop Med 2023; DOI:10.4103/1995-7645.368015
  2. Comparison of direct fluorescent test with real-time PCR to detect acute lower respiratory tract virus infections in children from May to July 2014, in a tertiary care hospital in Sri Lanka. Sri Lankan Journal of Infectious Diseases,

DOI: http://doi.org/10.4038/sljid.v12i2.8478

  1. Evaluation of the diagnostic performance of a commercial molecular assay for the screening of suspected monkeypox cases in Sri Lanka, Infectious Medicine,

DOI: https://doi.org/10.1016/j.imj.2023.05.002.

  1.  Adenovirus detection among children with severe acute respiratory symptoms admitted to a tertiary care hospital, Sri Lanka Collage of Microbiologists Bulletin. https://slmicrobiology.lk/slcm-bulletins/
  2. Seasonality of Respiratory Syncytial Virus from respiratory samples received at National Influenza Centre (NIC) , Sri Lanka Collage of Microbiologists Bulletin. https://slmicrobiology.lk/slcm-bulletins/
  3. Bacterial and viral aetiology of acute lower respiratory tract infection in a selected group of children admitted to a tertiary care hospital in Sri Lanka, Sri Lanka Collage of Microbiologists Bulletin, https://slmicrobiology.lk/slcm-bulletins/
  4. Comparison of direct florescent test with real time PCR for diagnosis of respiratory virus infection in children(OP19), The Bulletin of the Sri Lanka Collage of Microbiologists. https://slmicrobiology.lk/slcm-bulletins/
  5. Prevalence of types of Respiratory Syncytial Virus and association of types with disease severity in a selected group of children with acute lower respiratory infection , The bulletin of the Sri Lanka Collage of Microbiologists.
  6. Parainfluenza virus infection and prevalent subtypes of parainfluenza in a selected group of children with severe acute respiratory symptoms, The Bulletin of the Sri Lanka Collage of Microbiologists, https://slmicrobiology.lk/slcm-bulletins/
  7. Prevalence and genotype distribution of Human Papillomavirus in attendees at Central Sexually Transmitted Diseases Clinic, Sri Lanka. https://orcid.org/0000-0002-9920-4622
  8. Burden of Hepatitis B and C infection among high-risk groups and blood donors in Sri Lanka. https://orcid.org/0000-0002-3425-7635